Fully Enzymatic Synthesis (FES) of DNA

Synthetic DNA is the life force driving discoveries in clinical medicine, pharmaceuticals, agriculture, and food. But the chemical synthesis process we’ve come to rely on only produces short DNA oligos. That’s why we started an enzyme-based DNA synthesis revolution, so you don’t have to choose between fast turnarounds, oligo length, and purity.






Gene Editing


Design donor template DNA or long guides for a variety of CRISPR edit types including HDR knock-in, prime and base editing

Molecular Cloning


Long and traditionally “complicated” sequences currently unavailable  including high/low GC, long homopolymers and repetitive elements

Gene Assembly


Order gene fragments or large genetic constructs with high accuracy regardless of the difficulty of your sequence

Other applications? Consult with our experts to design DNA for your specific project


long icon


With our proprietary enzymatic synthesis technology, we can produce DNA >150 bases with ease.

pure icon


An in-process purification step yields clean DNA without the need for lengthy and expensive post-synthesis purification.

accelerated icon


The ability to produce long oligos directly without added purification steps means that we can deliver long, pure DNA faster.

The first Fully Enzymatic Synthesis (FES) technology from pioneers of DNA synthesis

Molecular Assemblies was founded by scientists who helped commercialize the chemical DNA synthesis process. Since then, these same scientists have been working to find a better method, turning to synthetic biology principles to evolve the terminal deoxynucleotidyl transferase (TdT) behind Fully Enzymatic Synthesis and the next generation of DNA writing.

Animated Polymerase Graphic Spinning in 3D

Evolved polymerase enables accelerated synthesis of long, pure oligos to drive synthetic biology

Transform Your Research With Fully Enzymatic Synthesis

Please provide us with a brief overview of your needs and a member of our dedicated team will reach out to discuss your project in detail, offering personalized solutions.

Request your quote today and redefine the boundaries of what’s possible tomorrow.