J. William Efcavitch, Ph.D.

Bill Efcavitch co-founded Molecular Assemblies in 2013 and serves as Chief Scientific Officer. He was a founding member of Applied Biosystems, as the company’s ninth employee. At Applied Biosystems, Dr. Efcavitch built and managed the research and development (R&D) group that led the commercialization of phosphoramidite oligonucleotide synthesis and the Models 380A, 380B and 381 DNA synthesizers. He spent 18 years at the company, managing the development of many successful biotechnology instrument and reagent systems, including the AB 1700 Expression Array System, Model 3900 DNA Synthesizer, ABI Prism Models 377 and 3700, ABI Model 310 DNA Analyzer, and the Model 230A Micro Preparative Electrophoresis System.

Dr. Efcavitch has held the positions of Senior Vice President of R&D at Affymetrix, and Senior Vice President of R&D and later Chief Technology Officer at Helicos BioSciences. At Helicos, he led the development of the HelicosĀ® Genetic Analysis System, the world’s first commercially available single molecule DNA sequencer. Dr. Efcavitch has also served as an independent consultant to several venture capital firms and biotechnology start-up companies. He is co-inventor of a flowable polymer for capillary electrophoresis DNA sequencing used in all Applied Biosystems’ capillary sequencers as well as virtual terminator nucleotides for single molecule DNA sequencing.

Dr. Efcavitch received his PhD in 1981 at Ohio University, where he studied with Dr. Thomas E. Wagner. He was also a post-doctoral fellow with Dr. Marvin H. Caruthers at the University of Colorado in Boulder.